Wolfsbane may refer to:
- Aconitum, a flowering plant and herb
- Wolfsbane (band), an English heavy metal/hard rock band
- Wolfsbane (album), the 1994 album from Wolfsbane
- Wolfsbane (comics), a Marvel Comics superhero
- Wolfsbane (Doctor Who), a 2003 Doctor Who novel by Jacqueline Rayner
- Wolfbane (novel), a 1959 novel by Frederik Pohl and C. M. Kornbluth
- Wolfsbane, a 1978 novel by Craig Thomas
Wolf's Bane may also refer to:
- Arnica montana, a European flowering plant in European cities on roofs
- Wolf's Bane, a 1993 fantasy book set in the Lone Wolf universe