Wolfson, in reference to an institution, may refer to:
- Wolfson College, University of Cambridge
- Wolfson College, University of Oxford
- The Wolfson Foundation, founded by Isaac Wolfson
- Wolfson Microelectronics, an electronics company
- Samuel W. Wolfson High School, a public high school in Jacksonville, FL
Wolfson or Volfson is a Jewish surname, and may refer to:
- David Wolfson, Baron Wolfson of Sunningdale (born 1935), British politician and businessman, nephew of Isaac Wolfson, former chairman of GUS and Next
- Elliot R. Wolfson, professor of Hebrew and Judaic studies at New York University
- Evan Wolfson, (born 1957), prominent American civil rights attorney and advocate
- Freda L. Wolfson (born 1954), United States District Judge in New Jersey
- Harry Austryn Wolfson, (1887–1974), professor of literature and philosophy at Harvard
- Isaac Wolfson, (1897–1991), British businessman and philanthropist, former chairman of GUS
- Leonard Wolfson, Baron Wolfson, (born 1927), British businessman, son of Isaac Wolfson, former chairman of GUS
- Louis Wolfson, (born 1912), Wall Street financier and a major thoroughbred race horse owner and breeder
- Mark Wolfson, (born 1934), German politician
- Mitchell Wolfson, Jr., (born 1939), businessman and founder of the Wolfsonian Museum
- Richard Wolfson (musician), (1955-2005), Israeli musician and journalist
- Richard Wolfson (physicist)
- Simon Wolfson, Baron Wolfson of Aspley Guise (born 1967), son of David Wolfson, chairman of clothing retailer Next
- Theresa Wolfson, (1897-1972), labor activist and educator
- Tracy Wolfson (born 1975), sports reporter
Woolfson is another variation of this surname, and may refer to:
- Eric Woolfson (1945-2009), Scottish singer and producer
- Michael Woolfson, (born 1927), British physicist
Wolfson may also refer to:
- the Wolfson History Prize, awarded by the Wolfson Foundation
- the Wolfson economics prize, a one-off 2011/12 contest on how best to exit the Eurozone