XS may refer to:
- Extra Small (XS), a size of clothing as defined in the European clothing-size standard EN 13402
- XS (comics), a DC Comics superheroine
- XS Energy Drink, an energy drink
- Xavier School, a secondary school in San Juan, Metro Manila, Philippines
- XS (band), a Russian all female pop-band
- Para-Ski XS, a Canadian powered parachute design
In computing:
- XS (Perl), an interface through which computer programs written in Perl can call C language subroutines
- XS (Game), a 1997 FPS game made by GT interactive
- Yamaha Motif, a series of synthesizers
- XS, a production server of EVS Broadcast Equipment
XS may also refer to:
- Cross section (geometry)
- Xiaolin Showdown