Surname
- The pioneer Zane family in the United States, which includes:
- Ebenezer Zane (1747–1811), American pioneer
- Betty Zane (1759–1823), sister of Ebenezer
- Alex Zane (born 1979), English television and radio presenter
- Arnie Zane (1947–1988), American dancer and choreographer
- Billy Zane (born 1966), American actor
- Carolyn Zane, American romance novelist
- Charles S. Zane, first chief justice of the Utah Supreme Court
- Clayton Zane (born 1977), Australian soccer player
- Frank Zane (born 1942), American bodybuilder and teacher
- Joe Zane (born 1971), American artist
- Lisa Zane (born 1961), American actress
- Matt Zane (born 1974), American musician
- Randolph Zane (1887–1918), American marine
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