Zasu may refer to:
- Zasu, Master of the seat, head of the temple (abbot) in Sōkan, the Japanese system of rankings for Buddhist clergy
- Zasu (horse)
- 1974 winner of the Champagne Stakes (Australia), a Group 1 horse race in Australia for two-year-old thoroughbreds
- 1975 winner of the Queensland Oaks, a Group 1 Australian thoroughbred horse race for 3 year old fillies at set weights
- Zasu, game developed by defunct company Enix
- Zasu Knight, actress in Buffy the Vampire Slayer adult parodies
- ZaSu Pitts Memorial Orchestra, formed in San Francisco by Stephen Ashman, recorded several LPs from 1984-1987 and continue to be active
- Zasu River or Yazoo River, a river in the U.S. state of Mississippi
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