OU or Ou or ou may stand for:
- University of Oklahoma, United States
- Oglethorpe University, United States
- Oakland University, United States
- Oakwood University, United States
- Ohio University, United States
- Olivet University, United States
- The Open University, United Kingdom
- The Open University of Hong Kong, Hong Kong
- University of Oregon, United States
- Osmania University, India
- University of Otago, New Zealand
- University of Ottawa, Canada
- University of Oxford, United Kingdom
- Ou (digraph)
- Ou (ligature) in the extended Latin alphabet
- O (surname), anglicized as Ō, (王), a Japanese family name
- Ou (surname) (區 or 歐), a Chinese family name
- Nam Ou, a river in Laos
- Ōu Mountains, Japan
- ʻŌʻū, a bird (Psittirostra psittacea)
- Croatia Airlines' IATA code
- Orthodox Union (Union of Orthodox Jewish Congregations of America)
- Organizational Unit
- Over unity, a phrase related to perpetual motion
- Our Ukraine (political party)
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