Health Effects
Styrene is regarded as a "hazardous chemical", especially in case of eye contact, but also in case of skin contact, of ingestion and of inhalation, according to several sources. The U.S. EPA has described styrene to be "a suspected toxin to the gastrointestinal tract, kidney, and respiratory system, among others." On 10 June 2011, the U.S. National Toxicology Program has described styrene as "reasonably anticipated to be a human carcinogen". However, a STATS author describes a review that was done on scientific literature and concluded that "The available epidemiologic evidence does not support a causal relationship between styrene exposure and any type of human cancer.". Despite this claim, work has been done by Danish researchers to investigate the relationship between occupational exposure to styrene and cancer. They concluded, "The findings have to be interpreted with caution, due to the company based exposure assessment, but the possible association between exposures in the reinforced plastics industry, mainly styrene, and degenerative disorders of the nervous system and pancreatic cancer, deserves attention." The Danish EPA recently concluded that the styrene data do not support a cancer concern for styrene.
The U.S. EPA does not have a cancer classification for styrene, but currently is evaluating styrene's cancer-causing potential through its Integrated Risk Information System (IRIS) program. The U.S. National Toxicology Program of the U.S. Department of Health and Human Services also currently is evaluating styrene's potential toxicity To date, no regulatory body anywhere in the world has classified styrene as a known human carcinogen, although several refer to it in various contexts as a possible or potential human carcinogen. The International Agency for Research on Cancer considers styrene to be "possibly carcinogenic to humans". Chronic exposure to styrene leads to tiredness/lethargy, memory deficits, headaches and vertigo.
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