Tuttle may refer to:
- Tuttle, Alberta
- Tuttle, California, in Merced County
- Tuttle, Colusa County, California
- Tuttle, Oklahoma
- Tuttle, North Dakota
- "Tuttle" (M*A*S*H), a 1973 episode from the television series M*A*S*H
People with the surname Tuttle:
- A. Theodore Tuttle (1919–1986), Mormon leader
- Archibald "Harry" Tuttle, a character played by Robert De Niro in the film Brazil
- Ashley Tuttle, musical actress and dancer
- Bill Tuttle (1929–1998), baseball player and public speaker
- Charles E. Tuttle (1915–1993), publisher
- Daniel Sylvester Tuttle, bishop of the Episcopal Church
- Dave Tuttle (born 1972), UK football manager
- Elbert Tuttle (1897–1996), US judge
- Elmo Tuttle, fictional comic strip character
- Frank Tuttle (1892–1963), film director and writer
- Fred Tuttle (1919–2003), farmer, actor, and candidate for the US Senate
- Gina Tuttle (born 1973), actress and voice artist
- Gregory Tuttle, fictional character in the TV series Chuck
- Herbert Tuttle (1846–1894), American historian
- Hiram A. Tuttle (1837–1911), Governor of New Hampshire
- Horace Parnell Tuttle (1837–1923), astronomer whose name is borne by an asteroid and several comets
- James Madison Tuttle, Union general in the Civil War and Democratic candidate in 1863 for Governor of Iowa
- Julia Tuttle (1849–1898), businesswoman, farmer, and "Mother of Miami"
- Karen Tuttle (1920–2010), viola teacher
- Lisa Tuttle (born 1952), author
- Lurene Tuttle (1906–1986), character actress
- Lyle Tuttle (born 1931), tattoo artist
- Matt Tuttle (musician), drummer
- Matt Tuttle (soccer) (born 1987), American soccer player
- Merlin Tuttle (born 1941), ecologist
- Perry Tuttle (born 1959), NFL football player
- Richard Tuttle (born 1941), postminimalist artist
- Rick Tuttle (born 1940), Los Angeles politician
- Robert H. Tuttle (born 1943), US ambassador
- Russell Tuttle (born 1939), primate morphologist and paleoanthropologist
- Steve Tuttle (born 1966), hockey player
- William G. T. Tuttle, Jr. (born 1935), U.S. Army general
- William J. Tuttle (1912–2007), make-up artist
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